A mysterious figure swathed in bandages and obscured by dark goggles rents a room in a small English inn during a snowstorm. The enigmatic man, a scientist, demands privacy as he feverishly conducts strange experiments. The inn's proprietors and local townsfolk grow suspicious of his bizarre behaviors and the strange, inexplicable events that begin to occur around him. His privacy fiercely guarded, the scientist's temper flares at intrusions, revealing a volatile and possibly dangerous character.

The reason behind the scientist's odd behavior and self-imposed isolation is revealed to be a result of his groundbreaking yet perilous discovery: a serum that renders him invisible. The power of invisibility, however lofty the original intentions, begins to have a corrupting effect on the scientist. As he descends into madness, the potential for its misuse becomes increasingly apparent, not only to the dismayed scientist but also to the surrounding community as fears mount and the threat of his newfound power spirals out of control.