In a small, remote American town, a top-secret government biolab develops biological weapons under the guise of agricultural research. The lab's head of security, Joanie Morse, is present when an accidental leak of a virulent biological agent occurs. The containment protocols are triggered, isolating the lab and imprisoning the team inside, with deadly consequences. Joanie must initiate quarantine procedures and soon realizes that any lapse in security measures could have catastrophic effects. Such an outbreak could potentially kill millions, driving home the importance of controlling the situation quickly and effectively.

As the authorities scramble to handle the situation, Sheriff Cal Morse, Joanie's husband, is brought in to help manage the crisis from outside the quarantine zone. With mounting pressure and lives hanging in the balance, he coordinates efforts with Dr. Dan Fairchild, a scientist familiar with the lab's dangerous activities. Together, they race against time to uncover the truth behind the lab’s real purpose and neutralize the threat before it escalates further. The unfolding terror and suspense highlight the blurring lines between those meant to protect and those potentially causing harm.