In Greenwich Village, Gillian Holroyd is a modern-day witch who leads a somewhat mundane life running an African art gallery. She becomes infatuated with her upstairs neighbor, Shep Henderson, who is just about to marry a snobbish socialite. Using her magical powers, Gillian enchants Shep to fall in love with her, meddling with his upcoming marriage. Her whimsical lifestyle is shared by her mischievous brother Nicky, also a warlock, and her eccentric Aunt Queenie, both of whom entertain themselves with their supernatural abilities.

As Gillian and Shep's relationship deepens, complications arise when Gillian starts grappling with her own feelings. The witch begins to feel genuine love for Shep, complicating the spell-induced affection she cast on him. Conflicted about revealing her true nature and the original enchantment, Gillian faces unexpected decisions about love and honesty. The story explores themes of magic and romance while intertwining moments of humor and tension. The unfolding events prompt Gillian to confront the implications of her actions on both their lives.