The story begins with the rise of a young Panamanian boxer, Roberto Durán, who emerges from a life of poverty with an incredible talent for fighting. His journey takes a pivotal turn when he meets Ray Arcel, a legendary boxing trainer who sees potential in Durán's raw skill and determination. Arcel, who had been away from the ring due to a mob-enforced exile, returns to coaching with the aim of shaping Durán into a world-class champion. Under Arcel's mentorship, Durán rapidly ascends through the ranks, earning a reputation for his aggressive style and indomitable spirit, and eventually secures a shot at the world lightweight title.

Durán's career reaches new heights as he conquers challenges both inside and outside the ring. His rivalry with American boxer Sugar Ray Leonard becomes the talk of the boxing world, symbolizing a clash of styles and cultures. As Durán faces increasing pressure from the media, public expectations, and his tumultuous personal life, his relationship with Arcel becomes strained. Balancing fame, family responsibilities, and his fierce ambition, Durán grapples with the immense weight of his newfound celebrity status. With his legacy on the line, he must navigate the complexities of success while staying true to his roots and the spirit that first drove him to fight.