In a small Tennessee town, Lazarus, a deeply religious farmer and former blues guitarist, is struggling to come to terms with his wife's betrayal. His life takes an unexpected turn when he finds Rae, a young woman with a troubled past, severely beaten and left for dead on the side of the road. Rae is known in the town for her promiscuity, which is partly a coping mechanism for her traumatic experiences and abandonment issues. Her boyfriend, Ronnie, who suffers from severe anxiety, has recently left for military service, exacerbating Rae's feelings of loneliness and vulnerability.

Feeling a moral obligation to help, Lazarus takes Rae into his home to nurse her back to health. Dissatisfied with her dangerous lifestyle and determined to mend her ways, Lazarus uses unconventional methods to keep her from further self-destruction. A unique bond forms between them as they share their stories and vulnerabilities. Lazarus finds a new purpose in helping Rae, seeing it as a way to redeem both of their lives. This unconventional relationship sets the stage for a journey of mutual healing, self-discovery, and redemption, against a backdrop of the Mississippi blues culture that shapes their environment and interactions.