A blind puzzle-maker and retired journalist, Franco Arno, overhears a suspicious conversation outside a medical research facility while walking with his niece. The same night, a break-in at the facility leads to the theft of a file. Shortly thereafter, a series of mysterious deaths begins, involving individuals connected to the medical institute, which is focused on genetic research. Arno’s heightened senses pick up clues missed by others, and his curiosity is piqued. Teaming up with an ambitious and sharp-witted reporter, Carlo Giordani, the unlikely pair delve into a complex web of intrigue and danger.

Arno and Giordani uncover a connection between the theft and the subsequent murders, revealing that they may be related to the institute’s controversial genetic studies that certain parties might want to be kept secret. As they draw closer to the truth, their investigation becomes increasingly perilous, attracting the attention of the killer. They navigate a labyrinthine plot of blackmail, corporate secrecy, and scientific ambition, which tests their wit and resolve. The stakes escalate when Arno and Giordani become targets themselves, as they race to unmask the murderer before becoming the next victims of this shadowy conspiracy.