Set in a mythic New York City at the turn of the 20th century, the story focuses on Peter Lake, a master thief on the run from his former boss, a ruthless gangster named Pearly Soames. Peter's life takes an extraordinary turn when, during a burglary, he meets Beverly Penn, a young woman dying of consumption. Despite the vast differences in their backgrounds and the dangers surrounding them, the pair quickly falls in love. This connection unlocks a hidden, magical world to Peter, revealing that he is central to a much larger, cosmic story. Faced with the power of eternal love and the menace of those who would thwart it, Peter and Beverly's bond is tested in ways they never imagined.

As Peter battles to save Beverly and come to terms with his own destiny, he encounters a series of unique characters, including a mysterious white horse that becomes his guardian. The narrative weaves through time, exploring themes of love, destiny, and the possibility of miracles. With Pearly and his minions relentlessly pursuing him, Peter's journey is fraught with challenges and revelations. The story delves into the deep connections between the characters, the nature of time, and the idea that love can transcend death, all set against the backdrop of a magical and transformative New York City.