John Hollar is a struggling graphic novelist living in New York City with his pregnant girlfriend, Rebecca. When he learns that his mother, Sally, has been diagnosed with a brain tumor and is scheduled for surgery, John reluctantly returns to his small hometown to support his family. Upon arriving, he finds himself thrust back into the chaotic world he left behind, dealing with his emotionally drained father, Don, and his overbearing brother, Ron. The family dynamics are strained, with old resentments bubbling to the surface as they navigate the tension and fear surrounding Sally's health crisis.

As John reconnects with familiar faces from his past, including his high school ex-girlfriend Gwen and her jealous husband Jason, he begins to confront unresolved issues and reevaluate his life choices. Torn between his responsibilities in New York and the needs of his family, John wrestles with finding a balance while supporting his mother's recovery. Along the way, he gains a deeper understanding of love, sacrifice, and what it truly means to be part of a family. Through laughter and tears, the Hollars learn to grow stronger together despite the challenges they face.