Grace, a newlywed, marries into the wealthy and eccentric Le Domas family, who have amassed their fortune through generations of game-making. On her wedding night, she is unexpectedly roped into a longstanding family tradition of playing a game at midnight. Grace draws a card that instructs her to play hide and seek, but soon discovers that this is no ordinary children's game. The family, armed with various weapons, must find and kill her before dawn, believing that failing to do so will bring a curse upon them.

As Grace runs and hides within the sprawling Le Domas mansion, she quickly learns the sadistic lengths her new in-laws are willing to go to protect their tradition and fortune. Tensions rise within the family as they bumble through their attempts at capturing her, leading to various mishaps and escalating violence. Throughout this deadly game, Grace exhibits cunning, bravery, and resourcefulness in her bid for survival. She must navigate not only physical threats but also the complex family dynamics and dark secrets that drive the Le Domas clan.