Barry Kane, a worker at an aircraft factory in California, is falsely accused of setting a fire that destroys the factory and kills his best friend. The true culprit, a man named Fry, leaves behind a clue -- a name, "Pat Martin," written on a note. Kane believes that finding this Pat Martin will lead to the man who framed him and clear his name. With no evidence to prove his innocence and the police on his trail, Kane goes on the run, determined to track down Fry and uncover the real saboteurs behind the factory fire.

Kane's pursuit leads him to New York, where he meets and reluctantly teams up with a young woman, Patricia, who initially doubts his story. Together, they embark on a dangerous cross-country chase that takes them through various iconic American locales. As they progress, Patricia starts to believe Kane's innocence and aids him in his quest for justice. Along the way, they uncover a deeper conspiracy that puts their lives at risk as they close in on the saboteurs who are planning another act of destruction.