Desperate for money to cover his wife's medical bills, Will Sharp, a decorated veteran, turns to his adoptive brother, Danny, who has a nefarious past. With few options left, Will begrudgingly involves himself in Danny’s latest criminal scheme: robbing a bank in downtown Los Angeles. Despite careful planning, the heist goes spectacularly wrong when they encounter unforeseen complications, resulting in a shootout with the police. With the bank surrounded and their escape routes cut off, the brothers' situation descends into chaos.

In the midst of their escape, the brothers hijack an ambulance, taking two hostages: Cam Thompson, a tenacious EMT, and a critically injured police officer clinging to life after the shootout. The ambulance becomes an unlikely getaway vehicle, with Danny and Will trying to negotiate and outmaneuver the relentless police pursuit that unfolds across the city. The high-speed chase pushes the boundaries of survival as the brothers navigate the moral complexities of their dire circumstance while the hostages' lives hang in the balance.