In a rugged and unforgiving wilderness set across various terrains of North America, three men from different backgrounds find their fates intertwined in a tale of survival and redemption. A seasoned trapper with a mysterious past, played by Tom Selleck, is on what he vows to be his last expedition. Along the way, he encounters a European explorer and naturalist, portrayed by Rutger Hauer, who is in pursuit of new discoveries and the thrill of the unknown. Their journey takes a turn when they come across a young survival expert, played by Steve Backshall, who is out to test his limits against the continent's fiercest challenges.

As their paths merge, the trio must navigate not only the physical dangers posed by the harsh and unpredictable landscape but also the personal demons that brought them to these remote places. Their journey through dense forests, towering mountains, and treacherous rivers becomes a quest for survival. They face off against predators, hostile environments, and their own limitations. The dynamic between the men is marked by moments of conflict, camaraderie, and personal growth, offering a glimpse into the human spirit's capacity to endure and adapt. As they delve deeper into the wilderness, they learn that the greatest challenges come not from the wild, but from within, forcing them to confront what it truly means to be alive in one of the planet's most untamed regions.