Tony Camonte, an ambitious and ruthless gangster in Chicago, rises swiftly through the ranks of the criminal underworld by taking over the territory of his boss, Johnny Lovo. With sheer determination and violent tactics, he expands his influence and control over the city's illegal alcohol trade during Prohibition. As Tony's power grows, he becomes increasingly reckless and unrestrained, drawing unwanted attention from both rival gangs and law enforcement. His intense devotion to his sister, Francesca, is a driving force behind many of his decisions, creating tension in his relationships and contributing to his downfall.

Tony's ambition alienates those close to him, including his loyal friend Guino and his lover Poppy, who become wary of his escalating aggression. His obsession with maintaining control puts him at odds with everyone around him and makes him a target for those seeking retribution. Amidst the power struggles and betrayals, the criminal empire Tony has built begins to crumble under the weight of its own corruption and violence. His insatiable desire for dominance ultimately leads him into a dire situation, reflecting the inherent consequences of his ruthless pursuit of power.