An unassuming and mild-mannered Uber driver named Stu picks up a fare who turns out to be a grizzled, tough-as-nails police detective, Vic, hot on the trail of a notorious and elusive terrorist. Stu is immediately sucked into a harrowing ordeal when he realizes that his passenger is on an intense mission to bring down the criminal who murdered his partner months earlier. The detective has just undergone LASIK surgery, rendering him temporarily visually impaired, and needs Stu's help to navigate through the city. Over the course of the day, Stu unwillingly becomes Vic's driver and sidekick as they follow leads and encounter various obstacles and dangerous situations related to the case.

Stu's focus as an Uber driver is maintaining his high rating and providing excellent customer service, but this goal quickly becomes secondary as he finds himself in a world of trouble. His desperation to keep his life and his Uber job intact leads to a series of comedic and action-packed misadventures. The mismatched duo must find a way to work together, despite their opposite personalities and the chaotic circumstances they find themselves in. As they close in on the criminal's location, they're forced to confront not only the bad guys but also the unintended comedy that arises from their partnership.