In a grim version of 17th century Moldavia, a witch named Asa Vajda and her servant Javuto are executed for sorcery and vampirism by Asa's own brother. Before her death, Asa vows revenge on her brother’s descendants and a sinister mask is hammered onto her face. Centuries later, two traveling doctors, Dr. Choma Kruvajan and his assistant Dr. Andre Gorobec, stumble upon Asa's grave. Their curiosity causes them to inadvertently revive the witch, setting off a chain of events that threatens the lives of the local family and the surrounding village.

Asa, now resurrected, begins her quest for vengeance and targets her doppelgänger descendant, Princess Katia, to complete her resurrection and regain her full power. Strange occurrences besiege Katia’s family, and the villagers’ fear is palpable as ancient superstitions resurface. Dr. Gorobec, smitten with Katia, resolves to protect her, while Dr. Kruvajan falls under Asa's malevolent influence. As the malign forces advance, the urgent struggle between the forces of good and evil intensifies, plunging the region into chaos and terror.