Deep into the era of the Cold War, the aging archaeologist and adventurer, Indiana Jones, finds himself once more drawn into a perilous quest that pits him against his old rivals. Faced with the rise of former Nazi scientists now working with the United States government and other insidious forces vying for power, Indiana must confront his own aging and the changing world around him. With whispers of a mysterious artifact known only as "the Dial of Destiny," Indiana's journey leads him into a labyrinth of intrigue and treachery.

Alongside Indiana is Helena, a resourceful and spirited young woman with a connection to his past. As the stakes rise and the nature of the Dial becomes clearer, the two allies delve deeper into a world brimming with enemies and moral ambiguity. Their adventure spans across various exotic locales, piecing together clues that can potentially alter the future. With their wits and resilience tested at every turn, Indiana and Helena must navigate the shadows of espionage and historical secrets, while wrestling with the implications of their actions in a world on the brink of great change.