In 1959, a time capsule is buried at an elementary school with drawings of the future created by the students. Lucinda, a girl who hears mysterious whispers, fills her sheet with a seemingly random sequence of numbers instead of a drawing. Fifty years later, the capsule is opened and the contents are distributed to current students, with Caleb, the son of MIT astrophysics professor John Koestler, receiving Lucinda's number sequence. John becomes intrigued by the numbers and, through his analysis, discovers that they accurately represent the dates, death tolls, and coordinates of major disasters over the past 50 years, with three forthcoming incidents predicted.

John's discovery propels him into a state of deepening alarm and obsession. He seeks out Lucinda's family, finding her daughter Diana and granddaughter Abby. As they try to warn the authorities about the impending disasters and grapple with their own skepticism, John becomes desperate to understand the ultimate purpose of the numbers. His quest to unravel the mystery leads him to confront questions of determinism, faith, and his responsibility to his own son, whose hearing impairment exposes him to mysterious whisper-like communication similar to Lucinda's before her death. With the next predicted disaster looming, John is thrust into a race against time to avert catastrophe and find a pattern within the chaos that could shed light on the fate awaiting humanity.