Army Rangers Joe Armstrong and Curtis Jackson are dispatched to a Caribbean island to investigate the mysterious disappearance of several Marines. Upon arrival, they discover a plot involving a nefarious drug cartel, led by the sinister Leo "The Lion" Burke. The cartel is kidnapping Marines to create an army of genetically engineered super ninjas by using advanced scientific techniques. Joe's exceptional ninja training becomes crucial as they delve deeper into the conspiracy, uncovering the disturbing extent of the cartel's operations.

As Joe and Curtis infiltrate Burke's secret fortress, they face numerous battles against heavily armed soldiers and highly trained ninjas. With time running out, they must rely on their combat skills and bravery to thwart Burke's plans and rescue the kidnapped Marines. The mission's stakes escalate as they encounter betrayal and danger at every turn, culminating in a final showdown that tests their resolve and strength.