After a disastrous blind date at Hooters, single parents Jim Friedman, a widower with three daughters, and Lauren Reynolds, a recent divorcée with two sons, vow never to see each other again. Their fates intertwine when both end up, through a series of coincidences, booking the same family vacation to Africa. Jim and Lauren, along with their children, are forced to share a suite at an upscale resort. Despite their initial animosity, they start to bond during various activities and adventures.

Over time, the blended family of seven begins to see the advantages of spending time together. Jim's daughters, missing maternal guidance, find a role model in Lauren, while Jim provides the fatherly influence that Lauren's boys need. As they navigate through safaris, romantic dinners, and heartwarming moments, their mutual animosity turns into respect and shortly thereafter, affection. The children also develop friendships amongst themselves, breaking down barriers and fostering a sense of family unity.