In the distant future, the desert planet Arrakis, also known as Dune, becomes the center of a galactic power struggle due to its exclusive supply of the universe's most valuable substance, "spice." This spice is vital for space travel, extending human lifespan, and enhancing mental abilities. When the noble House Atreides is granted stewardship over Arrakis by the Emperor, they are thrust into a dangerous political conspiracy. Duke Leto Atreides, his concubine Lady Jessica, and their son Paul must navigate the treacherous landscape of interstellar politics and the native Fremen's culture to secure their family's future.

Paul Atreides, burdened with great expectations due to his noble birth and a mysterious prophecy, struggles with his identity and destiny amidst the looming conflict. His mother, Jessica, a member of the secretive Bene Gesserit sisterhood with advanced mental and physical abilities, has trained Paul in their ways, unintentionally preparing him for the harsh realities of Arrakis. As the Atreides family settles into their new home, they become aware of the dangers posed by their rival House Harkonnen, who previously ruled Arrakis and seek to reclaim it. The young heir must rapidly mature to lead and protect his people while coping with visions of a future that entwine him with Arrakis and its people more deeply than he ever imagined.