In the American West during the late 19th century, a severe winter is forecast, sparking a desperate rush among miners to stockpile whiskey before the snow sets in. A large shipment of whiskey is being transported from Denver to the town of Denver City, promising potential chaos as various groups become aware of its journey. A temperance movement, led by a determined suffragette, sets out to intercept the shipment in hopes of promoting sobriety. Meanwhile, a tribe of Native Americans plots to seize the cargo for themselves, and a group of cavalrymen is tasked with ensuring its safe passage, unaware of the turmoil brewing ahead.

The situation becomes increasingly complicated as these diverse groups converge on the wagon train, each driven by their own motivations. The cavalry must navigate between protecting the shipment and managing the perilous clashes among the rival factions. The temperance group’s zeal collides with the miners' desperation and the Native Americans' ambitions, leading to a series of comedic and action-packed encounters laden with miscommunication and blunders. As tensions rise, alliances shift unpredictably, creating a chaotic yet humorous struggle over the fate of the whiskey. Through this tumultuous journey, characters must contend with their clashing ideologies and unforeseen obstacles while attempting to avert disaster and chaos.