A legendary director, after the success of his film "North by Northwest," grapples with studio skepticism and personal creative demons in looking for his next big project. Defying expectations and seeking to innovate, he sets his sights on a provocative and unorthodox subject: the real-life story of a grisly serial killer. At the time, such material is considered unworthy of serious cinematic effort and is frowned upon by the industry. In pitched battles with studio heads who refuse to finance the project, the director decides to take a significant risk. He bypasses studio backing altogether and finances the film himself, betting his reputation and financial security on its success. He enlists the support of his skeptical wife and long-time collaborator, who is an uncredited script doctor and a stabilizing force in his career and life.

During the making of the film, the director's obsession with the lead actress and the demands of creating a chilling and innovative thriller place strain on his health and marriage. His wife feels neglected and contemplates an affair while simultaneously battling to ensure his vision comes to life on the screen. The casting process is tricky, with the director offering the coveted lead actress role to a major star, despite the studio’s reluctance. The production faces numerous hurdles, including the director's covertly filmed segment, censor battles over the film’s shocking content, and the innovative use of music and special effects, all of which threaten to derail the project before it can be completed.