In a future where the human body has adapted to an artificial environment, resulting in new transformations and mutations, a performance artist named Saul Tenser showcases the metamorphosis of his organs in avant-garde shows. Alongside his partner Caprice, Tenser has embraced the rapidly-evolving nature of human biology by turning the removal of his spontaneously growing organs into a theatrical spectacle. The performances, which occur under the guise of artistic expression, draw the attention of a curious and intrigued audience eager to witness the beauty and horror of Tenser's bodily evolution firsthand. His unusual ability to grow novel organs makes him a subject of fascination and revulsion.

As this evolution phenomenon becomes more widespread, the government institutes a regulatory body named the National Organ Registry to track these biological anomalies. Two of their investigators, Timlin and Wippet, become obsessed with Tenser's performances and the potential implications of his condition. There is also a mysterious group that views the changes as the next stage in human development and believes that accelerating this progression is essential for the species' survival. Tenser becomes entwined with these subcultures while grappling with his own existential questions about the nature of humanity, evolution, and creativity. He navigates a society where the lines between biology, identity, and art blur, revealing deep-seated desires to both control and surrender to the transformative potential of the human body.