A skilled but morally corrupt hitman named Frank Kitchen finds himself trapped in a brutal cycle of violence and revenge. After completing a job and double-crossing some influential figures, Frank is captured by a vengeful but brilliant rogue surgeon named Dr. Rachel Jane, who has suffered a personal loss due to Frank's actions. As part of her twisted quest for retribution and to demonstrate her medical prowess, Dr. Jane performs a radical, involuntary gender reassignment surgery on Frank while he is unconscious, turning him into a woman. Awakening to this shocking transformation, Frank is devastated and filled with rage.

Now living in a body that feels alien, Frank embarks on a harrowing journey to find those responsible for his predicament and exact his revenge. He faces numerous obstacles, as he must navigate both the criminal underworld and the challenges that come with his new identity. Through relentless pursuit, brutal encounters, and a dogged determination to reclaim his life, Frank's goal is singular: track down Dr. Rachel Jane and make her pay for what she has done. Throughout his ordeal, Frank confronts questions of identity, justice, and redemption, all while striving to survive in a world that has dramatically shifted around him.