George Newman, a daydreamer with a knack for losing jobs, is given the chance to manage a failing UHF television station, Channel 62, by his uncle. Initially, George and his friend Bob struggle to find an audience, and the station appears destined for bankruptcy. However, things take a turn when George stumbles upon the idea for an unconventional children's show called "Uncle Nutzy's Clubhouse," starring himself as the zany host. His eccentric and absurd style soon begins to attract a loyal following. Meanwhile, George's hyperactive janitor, Stanley Spadowski, also becomes a surprise hit with his own show, "Stanley Spadowski's Clubhouse," where his earnest and goofy antics endear him to viewers of all ages.

As Channel 62's popularity skyrockets, it quickly becomes a threat to the ratings of the more established and unscrupulous rival station run by R.J. Fletcher. Determined to crush the competition, Fletcher employs various underhanded tactics to sabotage Channel 62's success. In the face of these challenges, George and his ragtag team of misfits must band together to create original programming and save their station from financial ruin. The battle for survival against corporate greed and the odds sets the stage for a comedic adventure filled with eccentric characters and imaginative parodies.