In a futuristic Paris, a new and lethal virus named STBO is spreading, transmitted through sex without emotional involvement. Marc, a seasoned criminal, becomes indebted to American gangsters who demand him to retrieve a valuable scientific formula that could solve the crisis, but Marc dies before he can fulfill the mission. His close friend, Alex, a young and aimless courier, reluctantly agrees to take up the task. He partners with Marc's former lover, Anna, and they quickly become ensnared in a web of crime, deceit, and passion. The duo sets out on a thrilling journey that involves a series of heists and intense confrontations as they seek the formula to escape their dangerous binds.

As Alex navigates through the underworld, he becomes increasingly drawn to Anna, sparking complex emotions that complicate their professional relationship. Meanwhile, Alex must also deal with Lise, his own emotionally neglectful girlfriend, which adds another layer of tension. As they get closer to their goal, they face escalating threats from both law enforcement and rival criminals. Their bond and resolve are tested as the pursuit for the formula intensifies, leading them into unforeseen challenges that blend elements of suspense, romance, and desperation.