In a dystopian Chicago, the faction-based society has been shattered, and the long-standing peace is easily disrupted by escalating conflicts. Following the dramatic events that unfolded previously, the protagonists feel compelled to escape beyond the imposing wall that has confined them and the rest of the citizens for generations. Once outside, they are taken into a mysterious agency known as the Bureau of Genetic Welfare. This institution has been monitoring Chicago and its inhabitants as part of an expansive experiment orchestrated by a complex genetic purity movement.

Upon arriving, the group is exposed to shocking new truths that challenge their understanding of the world and their places within it. They discover that the city and its faction system were part of an elaborate genetic trial to rectify the mistakes of society's ancestors, leading to the creation of genetically pure and genetically damaged individuals. Encountering advanced technology and a civilization that operates under very different principles, they must grapple with the information that they are part of a much larger and more disturbing reality than they ever imagined. As they seek to uncover the true purpose of their existence within the broader context of the Bureau's influences, they must decide whom to trust in a landscape of complex politics and power plays that could have far-reaching consequences for their former home and its inhabitants.