A team of scientists stationed on a remote tropical island investigates voodoo rituals practiced by the local natives. Despite warnings of an ancient curse, the scientists disrupt a sacred ceremony, leading to catastrophic consequences. The natives summon the dead through dark magic, unleashing a powerful and uncontrollable force of zombies. The few remaining scientists attempt to escape but are overwhelmed by the relentless horde, leading to their demise one by one.

Years later, a group of mercenaries accompanied by a scientist returns to the island, unaware of its gruesome history. They soon encounter the reanimated dead and must fight for their survival. As they explore the depths of the island, they uncover horrifying secrets hidden within, forcing them into a desperate battle against time and the undead. The ominous curse threatens to consume them as the boundaries between life and death blur beyond recognition.