Dr. Stephen Strange is a brilliant but arrogant neurosurgeon who, after a tragic car accident, loses the use of his hands. Desperate to heal and return to his former life, Strange exhausts all traditional medical options and wealth, but to no avail. His journey for a cure leads him to the mystical enclave of Kamar-Taj in Nepal, where he meets the enigmatic Ancient One. Under her tutelage, Strange begins to learn about the mystic arts, discovering dimensions beyond human comprehension and formidable magical abilities within himself. His initial skepticism transforms into a deepening respect for the mystical world, but his personal struggles and ego still linger as obstacles on his path to true enlightenment.

As Strange delves deeper into the mysteries of magic, he finds himself caught in a struggle between powerful sorcerers and dark forces threatening to consume the world. He must confront his inner demons and challenges while balancing his pursuit of knowledge with the responsibility to protect humanity. Strange's journey from a self-centered surgeon to a protector wielding immense mystical power forms the heart of the narrative, revealing themes of redemption, responsibility, and self-discovery.