In a dystopian future, Earth has been devastated by dragons that have emerged from a long hibernation beneath London's underground. These creatures quickly multiply and set fire to everything in their path, leading to the near extinction of humanity. Survivors, including Quinn Abercromby, who witnessed the first dragon emerge in his childhood, have retreated into fortified castles and small communities in a desperate attempt to outlast the relentless assault. Quinn, now grown, leads a group of survivors in the Northumberland countryside, focusing on agriculture and defense to sustain what remains of human society. Their existence is precarious, living under the constant threat of dragon attacks, as they attempt to reclaim a semblance of normal life amidst the apocalypse.

Enter Denton Van Zan, a rugged American and leader of a group of dragon hunters who have arrived in England. Van Zan believes he has found a way to kill the dragons and is on a mission to locate and destroy their only male, the key to their species' proliferation. With advanced military tactics and a fearless attitude, Van Zan's approach clashes with Quinn's more conservative survival strategy. The arrival of Van Zan and his team forces Quinn to confront his past fears and losses caused by these creatures. Together, they embark on a perilous journey that represents humanity's last stand against the dragons, aiming to end their reign of fire once and for all.