Sailor Ripley, a rebellious ex-convict, and Lula Pace Fortune, a spirited young woman, are madly in love and decide to flee from Lula's overbearing mother, who has hired a private detective and a hitman to track them down. As they embark on their road trip across the American South, they encounter a series of bizarre and dangerous situations, revealing both the sinister and surreal aspects of their world. Along the way, they are constantly pursued by law enforcement and other shady characters, including a man named Bobby Peru who has his own nefarious intentions.

The couple's journey tests the strength of their relationship and their resolve as they try to escape the clutches of Lula's mother and the chaos that surrounds them. With each encounter, Sailor and Lula become more entwined in a web of violence, deception, and dark secrets. As they navigate this treacherous path, they are forced to confront their pasts and make critical decisions about their future together. Their doomed romantic adventure is filled with unexpected twists and turns that build up to an intense climax, leaving their fate hanging in the balance.