After interfering with a classified S.H.I.E.L.D. mission, the vigilante Punisher is captured and brought into custody. Director Nick Fury assigns Black Widow to work with him on a new mission: to stop the sale of stolen technology to terrorist organizations by the evil organization Leviathan. As they infiltrate a black market auction, the duo uncovers a much larger conspiracy involving super soldiers and the augmentation of human abilities to superhuman levels.

Their mission leads them across various global locales, constantly battling mercenaries and super-powered adversaries. As they gather more intel, Black Widow and Punisher realize the true scale of Leviathan’s plans, which threaten global security. They must use their combined skills to outmaneuver and outfight this formidable enemy while dealing with the personal and moral complexities that arise from their starkly different methods and pasts. The journey tests their resolve and partnership, ultimately forcing them to confront not just their enemies, but their own personal demons and beliefs about justice and duty.