In a futuristic Detroit, the once-peaceful streets have descended into chaos, dominated by rampant crime and a new drug called "Nuke." Omni Consumer Products (OCP), the megacorporation that controls the city’s police force, announces plans to create Delta City, which would replace the crumbling urban landscape with a utopian metropolis. However, their plans are hindered by financial issues and public dissent. RoboCop, the cyborg law enforcer, continues his fight against crime but begins to experience troubling signs of identity crisis and malfunctioning directives. Meanwhile, a ruthless drug lord named Cain emerges as the main distributor of Nuke, posing a severe threat to the city's stability.

Amidst rising tensions, OCP initiates a project to develop a more advanced and obedient version of RoboCop known as "RoboCop 2," believing this new model will better serve their interests and facilitate the construction of Delta City. Dr. Juliette Faxx, an ambitious psychologist working for OCP, takes charge of the project, recruiting Cain’s criminal mind for the prototype. RoboCop faces numerous challenges, including battling his own deteriorating condition, dealing with corrupt corporate strategies, and confronting Cain’s escalating influence. The ensuing conflict pushes RoboCop to his limits as he strives to protect the citizens of Detroit and maintain his sense of justice amidst overwhelming odds.