In October 1962, the United States faces an unprecedented challenge when surveillance photos reveal that the Soviet Union is placing nuclear missiles in Cuba, just 90 miles off the coast of Florida. This discovery triggers one of the most tense standoffs in history, bringing the world to the brink of a nuclear war. The situation escalates as the U.S. demands the immediate removal of the missiles, while the Soviets refuse, claiming the weaponry is purely defensive. As military forces on both sides prepare for the worst, the fear of global annihilation looms large, setting the stage for a high-stakes game of diplomacy and strategic maneuvers.

In the midst of this crisis, the story follows key figures within the Kennedy administration, including the President himself, his brother, Attorney General Robert Kennedy, and key White House aide Kenneth O’Donnell. Together, they navigate the treacherous political waters, dealing with endless meetings, heated discussions, and back-channel communications. Their goal is to find a peaceful resolution without resorting to military action, which could potentially ignite the nuclear conflict. The team's efforts are focused on exploring every diplomatic channel and possible solution to diffuse the escalating tension with the Soviet Union, highlighting the complexity of leadership and decision-making under unprecedented pressure.