Bertram Pincus, a socially awkward and misanthropic dentist, experiences a near-death experience during a routine medical procedure. When he recovers, he finds himself cursed with the ability to see and communicate with ghosts. These spirits, unable to move on from the earthly realm, quickly learn of Pincus' unique ability and seek his help in resolving their unfinished business with the living. Among them is a suave but persistent ghost, Frank, who has a particular request: he wants Pincus to prevent his widow Gwen from marrying again, convinced that her new fiancé is not the right man for her.

Reluctantly, Pincus agrees to Frank's plan and sets out to sabotage Gwen's relationship, using the information divulged by Frank to get close to her. However, as he spends more time with Gwen, Pincus starts to develop feelings for her, putting him in a moral dilemma. His journey of self-improvement and interpersonal relationships is fraught with comedic missteps and heartfelt revelations. Meanwhile, his interaction with the spectral world forces Pincus to confront his own ghosts, including his penchant for isolation and disdain for human connections.