A series of UFOs emerge from Mars and head towards Earth, causing widespread panic and excitement. The U.S. government, led by the President, attempts to handle the situation diplomatically and organizes a welcoming party for the Martians. National security advisor, scientists, and other officials speculate on the intentions of the aliens, attempting to decipher their actions through communication attempts. When the Martians arrive, an extravagant public gathering is held in the Nevada desert. However, the encounter quickly turns chaotic and violent as the Martians reveal malevolent intentions, leading to a nationwide crisis.

In the midst of the Martian invasion, various stories unfold involving a diverse array of characters each dealing with the chaos in their own way. From a trailer home family in Kansas to a casino owner in Las Vegas, and even a talk show host struggling to make sense of the situation, the narrative weaves through their individual attempts to survive. Efforts to retaliate against the technologically superior Martians are fraught with peril and comedic missteps. As humanity grapples with the overwhelming threat, an unlikely hero begins to emerge, and a surprising method of counteracting the invaders starts to become clear.