The plot revolves around multiple intertwined stories set in the grim, crime-ridden Basin City. Dwight McCarthy is haunted by his past love, Ava Lord, who reappears in his life with a plea for help and a promise of rekindled romance. However, Ava's manipulative nature soon surfaces, leading Dwight into a dangerous game of deceit involving her abusive husband, Damien Lord, and her lethal bodyguard, Manute. Meanwhile, Marv embarks on a brutal quest for vengeance after waking up disoriented amidst a pile of dead bodies, piecing together the events that led to his blackout.

Elsewhere in the city, Nancy Callahan struggles with the loss of her protector, John Hartigan, and spirals into a self-destructive path while plotting revenge against Senator Roark, who she blames for Hartigan's death. Johnny, a cocky gambler, finds himself entangled in a high-stakes conflict with the same ruthless senator after a big win at the poker table. Each storyline intertwines to paint a broader picture of betrayal, corruption, and vengeance in the gritty noir landscape of Basin City.