In medieval Scotland, a brave and respected warrior receives a prophecy from a trio of witches predicting his rise to power as king. Consumed by ambition and spurred to action by his wife, he murders King Duncan to claim the throne. As he ascends to power, the guilt and paranoia of his violent acts begin to consume him and Lady Macbeth. Their relationship strains under the weight of their deeds, while they try to secure their rule amidst increasing political turmoil.

As dissent grows among the nobles, the newly crowned king becomes increasingly tyrannical and unhinged, turning on friends and foes alike in an attempt to secure his power. The prophecy that once fueled his ambition now haunts him, as he struggles to decipher its meaning and protect himself from perceived threats. His reign descends into a cycle of bloodshed and madness, setting the stage for a climactic confrontation that will determine the fate of the kingdom.