In Miami, former newspaper columnist Eliot Arnold stumbles into a chaotic chain of events when his son, Matt, becomes involved in a high school prank aimed at classmate Jenny Herk. Jenny's stepfather, Arthur Herk, is a shady businessman under investigation by the FBI. Things escalate rapidly when hitmen Henry and Leonard are sent to kill Arthur due to his embezzlement from his company. At the same time, two dimwitted criminals, Eddie and Snake, attempt to rob the Herk household, but stumble upon a mysterious metal case instead. The case turns out to contain a nuclear bomb, complicating the situation dramatically.

Amidst this turmoil, various characters intersect in increasingly frantic and absurd scenarios: FBI agents Greer and Seitz aim to take down Arthur, while officers Monica Romero and Walter Kramitz struggle to maintain order. As different factions chase each other and the bomb, a series of miscommunications and misunderstandings lead to comedic and chaotic outcomes. Ultimately, it becomes a race against time to prevent disaster while untangling the web of criminal activities and personal vendettas that brought everyone together.