Two young lovers, Mickey and Mallory Knox, embark on a violent killing spree across the Southwest. They are depicted as outcasts of society who have suffered traumatic childhood experiences that have left them deeply scarred. Despite their murderous actions, they are portrayed as star-crossed lovers united against a world that has mistreated them. Their path of destruction captivates the nation, as they leave a trail of bodies behind them. However, their notoriety is not unloved; a sensation-hungry media turns them into infamous celebrities, as they are glorified by the very society they disdain. This perverse fame only fuels their desire for chaos, pushing them deeper into their own distorted view of reality.

On the other side of the law, the pursuit to capture the notorious couple is led by a determined detective with his own questionable moral code. The media frenzy surrounding the killers becomes his obsession, as he grasps at the chance for his own claim to fame in the public eye. As the body count rises and the national interest grows, the characters find themselves in a twisted narrative crafted by their actions and the media's fascination with violence. The line between criminality and celebrity blurs, challenging the audience to reflect on the cultural impact of media sensationalism and the glorification of violence.