Fifteen years after a harrowing experience in a gingerbread house, siblings Hansel and Gretel have become feared bounty hunters dedicated to exterminating witches. All grown up, they are now revered for their prowess in tracking down and killing witches, a mission borne out of their childhood trauma. When the town of Augsburg experiences a spate of child abductions, the Mayor summons the duo to find the children and kill the witches responsible. Unbeknownst to them, they are about to face a threat much greater than they ever encountered. Hansel and Gretel's reputation has spread far and wide, making them a target for other dark forces.

As they delve into the mystery of the missing children, Hansel and Gretel encounter a variety of dark and grotesque witches, each more menacing than the last. But it's not just the witches that pose a threat; the siblings must also navigate the treacherous political landscape of Augsburg. Sheriff Berringer, whose authority is threatened by the bounty hunters' presence, conducts his own ruthless witch hunts, complicating the siblings' mission. Tensions escalate as the full moon approaches, a critical moment for the witches' secretive grand plan. With the threat growing and the townspeople’s lives hanging in the balance, Hansel and Gretel must confront their past and the true nature of their witch-hunting legacy.