In the tumultuous final days of the Ottoman Empire, a young Armenian medical student named Michael arrives in Constantinople to further his education. He becomes romantically involved with Ana, a sophisticated Armenian woman already in a relationship with an American photojournalist named Chris. As the political climate worsens, tensions escalate between the Armenian population and the ruling Ottoman authorities. Michael's commitment to become a doctor is tested as he faces growing atrocities against his people, forcing him to reconcile his love for Ana with his duty to his heritage and community.

As the empire's genocidal campaign against Armenians intensifies, Michael, Ana, and Chris find themselves struggling to survive amidst widespread chaos and violence. They navigate a treacherous landscape where loyalty and betrayal intertwine. While Michael seeks to protect those he loves and fulfill his oath to save lives, Chris uses his platform to document and expose the horrors they witness. Their lives become a harrowing journey filled with peril, hope, and unyielding determination as they each confront the realities of war and human suffering in their quest for survival and justice.