Kermit the Frog lives a peaceful life in a swamp until he encounters a Hollywood agent who encourages him to pursue a career in show business. Inspired by the possibility of making millions of people happy, Kermit sets off on a journey to Hollywood. Along the way, he meets and befriends several quirky characters including Fozzie Bear, Miss Piggy, Gonzo, and Rowlf the Dog. These new friends join him in his quest, each with their own dreams of stardom. However, Kermit also finds himself pursued by Doc Hopper, a villainous entrepreneur determined to make Kermit the spokesperson for his fried frog legs restaurant chain.

As Kermit and his newfound friends travel cross-country, they face numerous comedic challenges and adventures. Despite the various obstacles and attempts by Doc Hopper to capture Kermit, the group remains determined to reach Hollywood and realize their dreams. Throughout their journey, they are met with both help and hindrance from a variety of colorful characters. As friendships deepen and motivations are clarified, Kermit reflects on his mission and what it means to achieve success while maintaining integrity and solidarity amongst friends.