A blind screenwriter, Harry Caine, learns of the death of Ernesto Martel, a wealthy industrialist. This news triggers a series of flashbacks revealing Harry’s past when he was known as Mateo Blanco, a successful filmmaker. Mateo becomes entranced by the alluring Magdalena (Lena), an aspiring actress and the mistress of Ernesto. Despite Ernesto's possessive and controlling nature, Lena and Mateo fall deeply in love during the filming of a movie titled "Girls and Suitcases." Their affair is clandestinely filmed by Ernesto's son, who harbors his own affections for Lena.

As their secret relationship unfolds, they face numerous obstacles, including Ernesto’s wrath and manipulation. Mateo is aware that his involvement with Lena could not only jeopardize their safety but also his career. Tensions escalate as the lovers attempt to maintain their bond amidst the growing danger imposed by Ernesto’s vengeful pursuit. The events culminate in a tragic incident that irrevocably alters their lives and careers. Years later, Harry grapples with his past, confronting old wounds while seeking closure and a deeper understanding of the choices that led to his current existence.