A dangerous biochemical agent is released from a military base, turning people into bloodthirsty, disfigured zombies. Amidst this chaos, Cherry Darling, an exotic dancer, loses her leg in a violent altercation but is saved by her ex-boyfriend, Wray, a mysterious and skilled fighter. As they flee the ensuing epidemic, Cherry is equipped with a makeshift machine gun prosthetic leg and the duo bands together with other survivors, including a doctor named Dakota who is also running from her sinister, disloyal husband.

The group of survivors, fighting their way through hordes of infected, seek refuge and formulate a plan to escape to safety. As their situation grows dire, they uncover information hinting at the cause of the outbreak and potential cures. Even as tensions rise and their numbers dwindle, they remain united to face the ever-increasing threats. With their odds of survival diminishing, the remaining members must muster all their strength and wit to protect each other and find a way out of the nightmarish landscape.