In a world where monsters have been forced into hiding to avoid persecution from humans, Draculaura, daughter of Dracula, dreams of a place where all monsters can coexist peacefully. With the help of her close friend, Frankiestein, daughter of Frankenstein's monster, she sets out to create a sanctuary where monsters can embrace their unique identities. Together, they embark on an ambitious journey to find and gather other young monsters who share their vision of acceptance and unity. As they travel the globe, they invite different creatures to join their envisioned school, including Clawdeen Wolf, Cleo de Nile, and Lagoona Blue.

Their dream starts to take shape as they establish a school, which is named and designed to be a safe haven for every kind of monster. However, they face numerous challenges along the way, such as overcoming deep-seated fears and prejudices within the monster community itself. In addition to internal struggles, they must also protect their newfound haven from external threats that seek to destroy it. As the protagonists work tirelessly to overcome these obstacles, their dedication and spirit lay the foundation for a new generation of monsters who learn to accept themselves and each other. The establishment of the school marks the beginning of a new era for monsterkind, embodying hope, acceptance, and unity among all beings.