In a small Oklahoma town, a woman named Karen works at a plutonium processing plant. She struggles with the grueling conditions and safety hazards of her job, alongside her colleagues and housemates Drew and Dolly. The plant's management ignores numerous safety violations, prioritizing productivity over the health of their workers. After several alarming incidents of worker contamination occur, Karen becomes increasingly concerned about the radiation's potential impact on her health and that of her friends.

Determined to expose the dangers and negligence at the plant, Karen begins to gather evidence of safety infractions and mishandling of materials. Her commitment to uncovering the truth causes tension with Drew, who fears repercussions, and strains her already fragile relationship with him. As Karen digs deeper into the company's malpractice, she faces mounting opposition from both her supervisors and co-workers, putting her in significant personal and professional danger.