A young man from Iowa named Joe moves to New York City, lured by the dreams of opportunity in the bustling metropolis. Struggling to find affordable housing, he lucks into an apartment that seems too good to be true. However, he quickly discovers why his new home was easily obtainable—the apartment is overrun with a massive colony of cockroaches. Far from being ordinary pests, these roaches can talk and sing, much to Joe's initial horror. Despite their quirks, the roaches have an odd affection for Joe, as previous tenants have opted for extermination methods that have left lasting resentments among the insect population.

Joe grapples with his new life in the city while learning to coexist with his unique roommates. He aims to win over his love interest, Lily, a kindhearted and environmentally conscious young woman working for an urban garden project threatened by greedy developers. As Joe navigates city life, the roaches become both a nuisance and unlikely allies in his quest. Their mischief constantly derails his attempts to thrive but also brings unexpected help when he needs it most. Blending surreal humor with themes of friendship and adaptation, Joe's bond with his insect companions becomes a catalyst for personal growth in a city marked by loneliness and ambition.