Cleopatra is a special agent for the United States government, famous for her beauty, fashion sense, and fierce combat skills. She launches a successful mission to burn a large opium supply in Turkey, infuriating the notorious drug queenpin, Mommy. As retaliation, Mommy orchestrates a raid on a rehabilitation center run by Cleopatra’s friends, Reuben and Tiffany, aiming to discredit and dismantle their efforts to help addicts recover. Returning to the United States, Cleopatra decides to take down Mommy’s drug empire once and for all.

As Cleopatra tirelessly works to combat the city's drug epidemic, she faces relentless challenges from Mommy, who will stop at nothing to protect her lucrative business. The tension escalates as Cleopatra navigates through shootouts, car chases, and hand-to-hand combat scenarios. Armed with intelligence, street savvy, and sheer determination, Cleopatra enlists the help of various allies including Reuben and a community of citizens tired of being oppressed by the drug trade. She must use all her resources to confront and neutralize Mommy’s operations, bringing justice to the streets and securing a safe environment for those like her friends who seek a better life.