In a post-apocalyptic world, Earth has been invaded by blind extraterrestrial creatures with an acute sense of hearing, hunting anything that makes a sound and decimating much of humanity. The Abbott family—parents Lee and Evelyn, deaf daughter Regan, and sons Marcus and Beau—navigate this silent new world by communicating through American Sign Language, tiptoeing barefoot, and meticulously planning every action to avoid making noise. Tragedy strikes early when the youngest child, Beau, activates a noisy toy, leading to his swift and devastating demise at the hands of the creatures.

The family continues to survive in an isolated countryside farmhouse, using sand paths to muffle their footsteps and colored lights to signal danger. Lee tirelessly searches for a weakness in the creatures while also trying to provide a sense of normalcy and safety, particularly for his children. He builds a cochlear implant for Regan, hoping to restore some of her hearing, and takes Marcus on a trip to teach him how to gather food and fish, all the while strictly adhering to the silent lifestyle essential for their survival. Meanwhile, Evelyn faces the daunting reality that she will soon give birth, a process fraught with uncontrollable noise that will inevitably attract the predatory creatures. As they prepare for the imminent arrival, the delicate balance of their existence is continuously threatened by the omnipresence of the deadly aliens lurking just beyond their temporary haven.